The All Share Index closed 8.3% lower at 40,500.21 points.
Only three companies were in the green on Monday. Aspen gained 1.61%, Spar gained 1.47% and Tiger Brands gained 0.07%.
Naspers declined by 8.61%, Prosus declined by 7.85% and Impala Platinum declined by 18.71%.
The JSE reacted in pursuit of stock exchanges worldwide after the US Federal Reserve cut interest rates by one percentage point on Sunday night.
The S&P 500 fell 6% shortly after the opening of the New York Stock Exchange, the Dow Jones Industrial Index 10.7% and the Nasdaq 6.2%.
Meanwhile, the rand fell to R16.61 against the dollar